Synopsis
Like a comprehensive blueprint, USP 79>, when read in its entirety, provides a science-based roadmap to fulfilling its primary objective – preventing patient harm. When implementing the standards set forth in the chapter, deciding where to begin can be the most daunting step. It may be preferable to break a task as complex as the proper preparation of CSPs into smaller, easier-to-digest portions. For instance, perhaps the most basic aspect of a cleanroom’s daily life cycle is its cleaning and upkeep. Fortunately, the recently revised USP contains a robust section on “Cleaning and Disinfecting the Compounding Area,” providing a basis upon which to build your cleanroom cleaning protocols. cites environmental contact as a major source of microbial contamination, and cautions that “scrupulous attention”1 to cleaning and disinfection of compounding areas is required to minimize it. The chapter also states that all cleaning and disinfecting practices shall be included in written policies and procedures to be followed by all compounding personnel.
